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F-18 flortaucipir PET and postmortem assessment of Alzheimer disease neuropathologic changes
2020/06/08

Visual reads of [18F]flortaucipir positron emission tomography (PET) scans may accurately support a pathological diagnosis of Alzheimer’s disease (AD) according to a recent article published on JAMA Neurology. In this diagnostic study of 82 individuals with or without dementia, visual reads of F-18 flortaucipir PET scans corresponded with postmortem Braak stages V and VI levels of cortical neurofibrillary tangles and high levels of AD neuropathological change. Therefore, PET may increase the diagnostic accuracy and confirm the underlying neuropathologic changes of AD.

 

To read more please visit:

https://jamanetwork.com/journals/jamaneurology/fullarticle/2764329

Source: JAMA